Supplementation of Vitamin D in Patients with Sickle Cell Bone Disease: A D- bate or a Combate?
نویسنده
چکیده
After its discovery as a genetically inherited hemoglobinopathy one hundred years ago, finding a widely available cure for sickle cell anemia (SCA, HbSS) still remains a challenge and the disease requires multi-disciplinary theranostic approaches (Menaa et al., 2013; Menaa, 2014). Indeed, more effort and resources to promptly find alternative therapeutics and/or adjuvants (e.g. nutraceutics) to HU, the orphan Food and Drug Administration (FDA)-approved drug, are mandatory as a means of decreasing mortality, morbidity and improving quality of life among SCA patients (Hyacinth et al., 2010; Jackson et al. 2012; Menaa et al., 2013; Ozen et al., 2013; Menaa, 2014).
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